Scientific Forums


 

Add reply Start new topic Start new poll


> spread of cancer cells, Full story at http://www.physorg.com/news78762425.html
mott.carl
Posted: Sep 30 2006, 11:16 AM


Advanced Member
*****

Group: Members
Posts: 1435
Joined: 26-August 06

Positive Feedback: 35%
Feedback Score: -123


http://www.physorg.com/news78762425.html

the cancer cells use the scissors through of combinations of enzimes that permit altere the cellular membrane through of inversion of voltage and ions the if cut to give way to enter in the blood vassels,its synthetize several enzimesto get fot tentatives,get whether couple the receptors of cells,and get to penetrate in the other,as diffuse,its proteivns and enzimes to can encounter the correct "key" to calculs it size,it index of growth,and get exchange substances and nutrients,as well as altere the chemics and eletric permeability to live in inospit ambient.all that if must it maleability and all "memory" of the normal cells-then think that exist "stem cell" that is,oncogens,that produces all the mechanism to the cells obtain all that need.then these oncogens stem cell have all capacity9WITH THE BREAK OF ITS HIDDEN VARIABLES)that permit it get win to all barrier moleculares and other.thence the reason of its have methastasis.are there hidden symmetris.
Top
Matador
Posted: Jan 20 2012, 01:31 PM


Advanced Member
*****

Group: Power Member
Posts: 873
Joined: 11-August 09

Positive Feedback: 95%
Feedback Score: 46


smile.gif


--------------------
Banned by Administration
Top
Robittybob1
Posted: Jan 20 2012, 07:29 PM


Advanced Member
*****

Group: Power Member
Posts: 6588
Joined: 15-October 11

Positive Feedback: 0%
Feedback Score: 0


Top
Matador
Posted: Jan 20 2012, 10:43 PM


Advanced Member
*****

Group: Power Member
Posts: 873
Joined: 11-August 09

Positive Feedback: 95%
Feedback Score: 46


Molecular scissors help cancer cells break out and spread
September 29, 2006

A University of Michigan research team has identified how cancer cells employ a sort of molecular scissors to cut their way out of tumors and begin spreading throughout the body.


QUOTE
This spread of cancer cells, called metastasis, marks a turning point in the progression of the disease, after which treatment and recovery become more difficult.

"We asked how cancer cells cut their way through tissues," said Stephen Weiss, Life Sciences Institute research professor and division chief, molecular medicine and genetics in the U-M Medical School. "They use what we call proteases, a type of molecular scissors. However, there are so many different types of these scissors encoded by the human genome, we wanted to focus our attention on finding the subset used by cancers."

In all forms of cancer, a hallmark of malignancy is the tumor's ability to penetrate the basement membrane, a specialized connective tissue that lines the internal and external surfaces of the body including blood vessels, nerves, muscle and fat. Of the more than 500 enzymes that could be used by cells as molecular scissors, the Weiss team found that three proteases, termed MT1-MMP, MT2-MMP and MT3-MMP, are the most likely candidates that regulate cancer cell invasion.

The tumor cells appear to use these three enzymes to cut their way through the basement membrane, thus allowing cancer cells access to blood vessels which act as conduits for the spread of malignant cells to distant sites in the body.

"These closely related proteases allow cancer cells to start eating through basement membranes and the surrounding tissues," Weiss said. "This is the first critical step in the malignant process and allows the rapid spread of cancer cells through the body."

By identifying this set of proteases, the studies by Weiss and his colleagues have provided the first known proof that a small set of genes and proteins may underlie the cancer cell metastatic process. While their work is still at an early stage, the researchers are attempting to develop new inhibitors of these proteases so that they could test their importance in animal models of human cancer.

"A cancer cell metalloprotease triad regulates the basement membrane transmigration program," by Kevin Hotary, Xiao-Yan Li, Edward Allen, Susan L. Stevens and Stephen J. Weiss, appears as an advanced online publication in the journal Genes & Development and in print on Oct. 1, 2006.

Source: University of Michigan




http://www.physorg.com/news78762425.html


You may as well post the info in here. I hate clicking links.


--------------------
Banned by Administration
Top
Capracus
Posted: Feb 3 2012, 12:31 PM


Advanced Member
*****

Group: Power Member
Posts: 5375
Joined: 5-October 06

Positive Feedback: 75.56%
Feedback Score: 41


QUOTE (kenneth26 @ Feb 1 2012, 10:52 AM)
Useful information  comes out through this post.
Are you referring to the previous posts on cancer pathology or the link to your soap website?
Top
Nudofan
Posted: Feb 6 2012, 02:32 AM


Unregistered









Cancers enter the bloodstream in microscopic amounts

Cancers can be caused by carcinogenic aromatics chemicals: BPA's, food additives, preservatives, pesticides, perfumes.............................

Cancers can be caused by yet unknown undetectable viruses in the bloodstream.

Cancers can be caused by UV radiation.

Have soldiers returning home from war wounds shown a larger incidence of cancers down the track years later than unwounded soldiers? From `Massive Blood Transfusions'
Top

Topic Options

Add reply Start new topic Start new poll


 

Terms of use