Life's Drive And Purpose, Choice Of Our Life's Purpose Is OURS

All things are Space, in motion.



g.

OOOh look another drive by

OOOh look another drive by

Re "The Structure Of The Genome"

A. Researchers used the gene encoding IgH, immunoglobulin heavy chain locus, generator of diverse kinds of antibodies, to demonstrate the structure of the genome.

http://www.physorg.com/news127746791.html

“The resulting structure shows that the antibodys gene is organized into ‘flower-like’ structures that are connected by linkers. These flowers contain the various parts that ultimately generate the wide variety of antibodies. This is the first time that geometry has been used to determine the structure of a genetic locus. Ultimately, the same approach should be used to elucidate the structure of the entire human genome.”


B. Relevant terms:

Exon : the polynucleotide sequence that codes information for protein synthesis and that is copied and spliced together with other such sequences to form messenger RNA.

V(D)J : B cells synthesize and secrete antibodies, high-affinity immunoglobulins. Somatic hypermutation is a mechanism for achieving diversification of immune responses in mature B cells. Antibody genes are modified in such cells in germinal centers, in a part of the lymph node where lymphocyte proliferation and maturation takes place and where T-cells are "educated" to recognize target antigens, invaders. The mutations are effected by recombination of the variable (V), diversity (D), and joining (J) segments of the gene, thus altering immunoglobulin expression.

The (1) subnuclear location and (2) chromatin state of the immunoglobulin heavy-chain (IgH) locus have been implicated in the control of V(D)J recombinations.


C. Background: Genes that control the immune system, Antibody genes, Structure of the immunoglobulin heavy chain locus (Igh)

http://en.wikipedia.org/w/index.php?title=...oldid=196689267


D. "The genome stores genetic information"

The work report refers to "...the genome is the most essential part of the cell for storing and accessing genetic information..."

This to me is like stating "... the team of astronauts is the most essential part of the space station for storing information about the constitution and functions of the space station...".

Strange conception of and reference to an organism, the genome, within its organ, its multi-functional skin, its outer cellular membrane...


Dov Henis

What Life Is Not And what Life Is

A. Definition of life that "truly captures the essence of what all living things actually are and do"?

http://www.newscientist.com/blog/space/200...fe-defined.html

This "new definition of life" seems to me like an engineer's definition of a train:

"Life is a thermodynamically open chemical system with a semi-permeable boundary. It contains an information-based complex system with emergent properties, part of which drives a metabolism based on a proton gradient. The said gradient generates the necessary potential difference across the semi-permeable boundary. The information is heritable and coded in such a way as to allow variation and thus evolution."


B. "life Is Destined To Become More Complex"?

http://www.bath.ac.uk/news/2008/3/17/ruleevolution.html

Seems to me that Earht's life is NOT "destined to become more complex" but that it evolves to enhance and maintain the energy stored in Earth's biosphere, Plain And Simple, and that like other temporarily constrained energy pockets (f.e. black holes) it will eventually undergo "energetic evolution".


C. "Viruses arose from the cellular domain...not long after the archaea"

http://www.physorg.com/news124097235.html

"The new analysis also indicates that viruses emerged not long after the archaea, with the superkingdoms eukarya and bacteria following much later – and in that order. This finding may influence the ongoing debate over whether viruses existed prior to, or after, the emergence of living cells, Caetano-Anolles said."

Seems to me that Viruses, Too, Are Bona Fide Organisms.


D. Repeating Ad Absurdum Plain Common-Sense Science Comprehensions

1. http://www.physforum.com/index.php?showtop...65&#entry320236

"Base Darwinistic" evolution starts at Life's day one, with pre-Archaea Genes, with the genesis on still un-biotic Earth of pre-genomed pre-celled genes.

2. http://blog.360.yahoo.com/blog-P81pQcU1dLB..._Q--?cq=1&p=372

Viruses, Too, Are Bona Fide Organisms. Evolution is in the direction of more effective survivability; this is not always the direction of more complexing for coping with changing environments and competition. In a stable nutritious environment, like in Earth's oceans, coping with vital requirenments, evolution, is in the opposite direction, simplify tooling and means.

It is plain common sense that viruses, even Viroids and Virusoids, nothing more than single strands of DNA or RNA, sometimes only 200-300 nucleotides long, are organisms as alive as we are, evolved at life genesis era and selected for survival in forms, composition and capabilities by living, and even replicating, off their richer kin. Smart little buggers.

3. http://blog.360.yahoo.com/blog-P81pQcU1dLB..._Q--?cq=1&p=409

Factors Involved In Extended Historical Darwinism:

- Earth Life Is A Real Virtual Affair; it pops in and out of existence in its matrix, which is the energy constrained in Earth's biosphere .

- Genes are organisms, interdependent members of genes communes, genomes, all continuously undergoing evolution directed towards survival as long as possible, for maintaining Earth's biosphere at a bio state as long as possible.

- "Culture" (= the totality of ways of the organisms' dealing with its environment: reaction to, manipulation of, exploitation of) is a ubiquitous biological entity, the major effector of genetic evolution, of capabilities and attributes selected for survival.

- The major course of natural selection is not via "random mutations followed by survival", but via interdependent, interactive and interenhencing selection of biased replication routes by genes at their alternative-splicing-steps junctions, effected by the cultural feedback of the second stratum multicells organism or monocells community to their prime stratum genes-genome organisms.

- Evolution of life is but a minute component of the evolution of the universe. Cosmic evolution is the evolution of energy. Life, like all objects and processes and natural laws in the universe, are - since none in exsistence at singularity - products of evolution and are continuously further evolving. Everything in the cosmos is fractal, rehappens on many scales, and is continuously evolving. Each and every system in the universe continuously evolves within the total universal evolution and all the systems' evolutions are intertwined and within it life's evolution is the evolution of genes-genomes, in an eventual losing attempt to survive, to maintain - as long as possible - pockets of constrained energy that would otherwise and anyhow eventually expand and dilute with the whole mass and energy of the cosmos...


Dov Henis

Puzzled why even Darwinians do not comprehend that Darwinism starts all the way back with Life's day one, with the pre-archaea not-yet-genomed-celled genes...

Equally puzzled why people use such terms as 'Darwinians'?

What about 'Jesusists' (or is that 'Jesuits' pretending not to be 'ss'?), or 'Einsteinians'? - Are you hoping for a following of HenisDovists? (And, can I use that in a book? )



g.

Hebrew is my native language. English acquired by study.

A. 1965 Webster:

-ian or -ean: skilled in or specializing in


B. "...hoping for a following of HenisDovists? (And, can I use that in a book?)"

- At my age I'm just hoping for next 'normally active' year...

- Use what in what book?


C. But seriously, re my life-science-news persistent critical following, it is simply a grudge against the fundamental political science guilds...

Dov Henis

Well, if you think that being 'normally active' is a case of having 'grudges', you merely have my symapthy.



g.

ZOOOOOMAnother meaningless zero content drive by....

This post has been edited by deadbeat on Apr 29 2008, 10:13 AM

Compact Galaxies In Early Universe Pack A Big Punch

http://www.physorg.com/news128692030.html


Again, repeating an old posting of mine:

"Singularity and D-Infinity (max expansion/ cosmic energy dilution) are the two cosmic stable states. Their in-between is a metastable state, which is an everyday commonsense observation. Likewise is the observation that the denser the compacting goal of material the more energy is required, and vice versa the more thorough the disintegration of material the higher the amount of energy released. It seems that E=mC^2 is a specific case of the cosmic (and universal) process
E=Total[m(1 + D)] where D is the Distance from Big Bang point and the sum is of all spatial values of D from D=0 to D=selected value.

BTW, following Newton (1) gravity is decreased when mass is decreased and (2) acceleration of a body is given by dividing the force acting upon it by its mass. By plain common sense, best scientific approach, the combination of those two 'laws' may explain the accelerating cosmic expansion of galaxy clusters, based on the above E/ m/ D suggested relationship. "


Thus the young "condensed galaxies" are, in fact, what later evolved into galactic clusters.

Dov Henis

Galaxy Clusters Evolved By Breakdown, Not By Buildup


At the absence, so far, of a protest re the conclusion of my last posting, here is a follow-up:

A. Genesis

http://blog.360.yahoo.com/blog-P81pQcU1dLB..._Q--?cq=1&p=268

Extrapolation of the expansion of the universe backwards in time to the early hot dense "Big Bang" phase, using general relativity, yields an infinite density and temperature at a finite time in the past.

At age 10^-35 seconds the Universe begins with a cataclysm that generates space and time, as well as all the matter and energy the Universe will ever hold.


B. How did galaxy clusters evolve

1. http://herschel.jpl.nasa.gov/galaxies.shtml

"Among the stranger objects that appear to have populated the early universe are active galactic nuclei (AGNs)."

2. http://imagine.gsfc.nasa.gov/docs/features.../evolution.html

"How did the Universe evolve after the Big Bang?" and "How did galaxies form?" These are big questions, and they are not easy to answer: after all, these things occurred billions of years ago. Galaxy clusters provide one window into the very early Universe. They are the largest gravitationally bound objects in the Universe, and the properties of clusters can be used to place strong limits on cosmological theories of structure formation and evolution.

3. http://www.sciencedaily.com/releases/2008/...80331122543.htm

The process of galaxy formation largely is a mystery. Current theory is that large galaxies formed over time from the interaction and merging of smaller galaxies. This process began more than 12 billion years ago, shortly after the Big Bang. Scientists have observed galaxies merging over a large range of distances and time, providing hard evidence to reinforce the theory. However, using current technology, it is difficult to detect this process at the most extreme distances, when galaxy formation was in its infancy.

Scientists believe galaxy clusters form in a similar manner. As galaxies congregate and interact in large, dense regions of space, the cluster grows with time. Witnessing this process first-hand helps scientists confirm their theory and deepen their understanding of the universe. Galaxy clusters can be detected at extreme distances with current technology because they are bright, but they are difficult to find.


C. Galaxy Clusters evolved by breakdown of "condensed packs",

not by accretion of smaller matter. The breakdown followed the relationship E=Total[m(1 + D)] , i.e. it was accompanied by an overall decrease of mass. Accretion possibly and probably took place, too, in cosmic evolution, but the GC evolved as D increased accompanied by m decreased.


Suggesting,

Dov Henis

Dark Matter And Energy, And Accelerating Expansion

A. Wikipedia

"Dark matter is a hypothetical form of matter that does not emit or reflect enough electromagnetic radiation to be observed directly, but whose presence can be inferred from gravitational effects on visible matter. According to present observations of structures larger than galaxies, as well as Big Bang cosmology, dark matter accounts for the vast majority of mass in the observable universe."

"Dark energy is a hypothetical form of energy that permeates all of space and tends to increase the rate of expansion of the universe. Assuming the existence of dark energy is the most popular way to explain recent observations that the universe appears to be expanding at an accelerating rate. In the standard model of cosmology, dark energy currently accounts for almost three-quarters of the total mass-energy of the universe."


B. Re-repeat old posting

"Singularity and D-final (max expansion/ cosmic energy dilution) are the two cosmic stable states. Their in-between is a metastable state, which is an everyday commonsense observation. Likewise is the observation that the denser the compacting goal of material the more energy is required, and vice versa the more thorough the disintegration of material the higher the amount of energy released. It seems that E=mC^2 is a specific case of the cosmic universal process
E=Total[m(1 + D)]
where D is the Distance from Big Bang point and the sum is of all spatial values of D from D=0 to D=selected value.

Per Newton (1) gravity is decreased when mass is decreased and (2) acceleration of a body is given by dividing the force acting upon it by its mass. By plain common sense, best scientific approach, the combination of those two 'laws' may explain the accelerating cosmic expansion of galaxy clusters, based on the above E/ m/ D suggested relationship."


C. Tieing Dark Matter, Energy, And Accelerating Expansion

At genesis, at age 10^-35 seconds, the Universe begins with a cataclysm that generates space and time, as well as all the matter and energy the Universe will ever hold.

Therefore in E=Total[m(1 + D)] m decreases as D increases since genesis.
What is the implication of the ever decreasing m?

m does not "disappear"; mass is a form of energy, energy being the base element of the cosmos, and the extent of energy and mass of the cosmos are constant.

The right-hand side of the above equation is a measure of the "dilution of universal mass" as the universe expands. Its implication is that on the route from singularity to a future final D, of maximum cosmic density to maximum cosmic expansion-dilution, there are transient or stable phase forms of mass and energy with which we are not yet familiar.


Dov Henis

This post has been edited by HenisDov on May 8 2008, 06:45 AM

What is 'wind'?

What substance of its own has it?

- Is it not just the motion of what exists?


And what substance of its own has a 'wave'?

- Is it not also simply the motion of other 'substance'?



'Life', as we currently judge it to be, is a more complicated ('evolved' - many 'parts' accumulated) motion of what exists.




g.

This post has been edited by Gorgeous on May 8 2008, 10:59 AM

Nature, Origin And Function Of Life

Dear g.

I guess there is an intended "profundity" in the above statement, even if I fail to fathom it.

I would similarly fail to fathom the profundity of a statement that a car has motion of what exists, which is evolved, comprising many parts, since I think I know how the car evolved.

Re Earth Life, my concepts of its nature, origin and function are amply presented in this thread and in additional postings elsewhere; I regret that those concepts, and their written formats, are unacceptable by organized "scientists" guilds...

Respectfully,

Dov Henis

No, it is really simple.

If you fail to fathom the really simple, what chance the truly profound?



g.